Author/Editor		Kocijančič, Andreja
Title		Osteoporoza: diagnostika in zdravljenje
Translated title		Osteoporoza: diagnosis and management
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 50, št. 1
Publication year		1999
Volume		str. 1-6
Language		slo
Abstract		Osteoporosis is a systematic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue, with a cosequent increase in bone fragility and susceptibility to fracture risk. Common sites of fracture are the spine, wrist and hips. The use of bone density measurements is of central importance for diagnosis of osteoporosis. The majority of peak bone mass is geneticaly determined. However the dietary calcium intake and physical activity during childhood and adolescence are associated with greater bone mass in early adulthood. Primary prevention of osteoporosis is aimed at young subjects by increasing peak bone mass. Secondary prevention of osteoporosis is the hormone replacement therapy, which will prevent bone loss at the menopause and thereafter. Pharmacological agents used in the treatment of osteoporosis aim mainly at reducing bone resorption or stimulating bone formation. The patient is advised to take regular physical activity to prevent the falls by increasing postural stability and mobility.
Summary		Osteoporoza je pogosta kronična sistemska bolezen skeleta, ki prizadane predvsem starejše ženske. Pri napredovani osteoporozi pride do zlomov. Najpogostejši osteoporotični zlomi so zlomi vretenc, kolka in zapestja. Diagnozo osteoporoze napravimo s pomočjo merjenja mineralne gostote kosti. Preventiva osteoporoze prične že v dobi odraščanja, ko lahko s pravilno prehrano in telesno dejavnostjo dosežemo višek kostne mase, ki je pri posamezniku gensko opredeljena. Sekundarna preventiva z nadomeščanjem spolnih hormonov je možna pri ženskah, takoj po menopavzi. Za zdravljenje že razvite osteoporoze uporabljamo sredstva, ki zavirajo resorpcijo kosti in sredstva, ki pospešujejo gradnjo nove kosti. V prizadevanju, da bi zmanjšali število osteoporotičnih zlomov poleg medikamentoznega zdravljenja osteoporoze poskušamo izboljšati koordinacijo gibov in zmanjšati število padcev oz. jih omiliti.
Descriptors		OSTEOPOROSIS BONE AND BONES CALCIUM VITAMIN D EXERCISE ESTROGENS CALCITONIN FLUORIDES BONE DENSITY