Author/Editor		Cilenšek, Jana; Kozjek, Franc
Title		Porazdelitev učinkovin v bolnikovem organizmu
Translated title		The distribution of active substance in human body
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 50, št. 4
Publication year		1999
Volume		str. 489-93
Language		slo
Abstract		The apparent volume of distribulion is a pharmacological parameter that tells us how an active substance is distributed in the body. It is an expression of the ratio of the quantity of an active substance in the body to its plasma concentration and helps us determine the optimal dosage regimen in an individual patient; i.e. the optimal dose administered at appropriate dose intervals. In cases of intoxication, data on distribution volumes of active substances and other compounds serve as a guide in preparing the therapeutic plan for detoxification.
Summary		Navidezni volumen porazdelitve je eden od farmakokinetičnih parametrov, ki nam pove, kako se učinkovina po telesu porazdeljuje. Podaja nam razmerje med količino učinkovine v telesu in njeno koncentracijo v plazmi. Pomaga nam, da bolniku odredimo optimalen režim doziranja: optimalen odmerek ob ustreznem časovnem intervalu doziranja. Pri različnih zastrupitvah nam poznani volumni porazdelitve učinkovin ali drugih spojin pomagajo pri pripravi načrta detoksikacije.
Descriptors		PHARMACOKINETICS