Author/Editor		Kanič, Vojko
Title		Antagonisti receptorjev angiotenzina II v kardiologiji
Translated title		Angiotensin II receptor antagonists in cardiology
Type		članek
Source		In: Hojs R, Krajnc I, Pahor A, editors. Zbornik predavanj in praktikum 11. srečanje internistov in zdravnikov splošne medicine Iz prakse za prakso z mednarodno udeležbo; 2000 maj 19-20; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2000
Volume		str. 263-74
Language		slo
Abstract		The effects of angiotensin II are mediated by angiotensin II receptors. Clinically important are receptors type 1 (AT1) and type 2 (AT2). All known clinical effects are mediated by AT1 receptors. The physiological role of AT2 receptors is not completely understood. Angiotensin II receptor antagonists are as effective as other groups of drugs in antihypertensive treatment, but almost without side effects. They are supposed to have a favorable effect on atherosclerosis. In patients with congestive heart failure, angiotensin II receptor antagonists are as effective as inhibitors of angiotensin converting enzyme. The combination of inhibitors of angiotensin converting enzyme and angiotensin II receptor antagonists in patients with congestive heart failure, after myocardial infarction and in renal insufficiency is still under investigation.
Descriptors		RECEPTORS, ANGIOTENSIN ANGIOTENSIN II HYPERTENSION HEART FAILURE, CONGESTIVE ANGIOTENSIN-CONVERTING ENZYME INHIBITORS