Author/Editor     Jan, J; Vrecl, M; Pogačnik, A; Bavdek, SV
Title     Tissue distribution of planar and non-planar chlorobiphenyls, 4,4'DDE and hexachlorobenzene in sheep and lambs
Type     članek
Source     Chemosphere
Vol. and No.     Letnik 38, št. 11
Publication year     1999
Volume     str. 2607-12
Language     eng
Abstract     The bioconcentration and distribution pattern of individual PCB congeners (IUPAC Nos: -54, -80, -155 and -169) and organochlorine pesticides (HCB and 4,4'-DDE) in blood, adipose tissue, liver and brain were examined in sheep two months after administration and in their offspring continuously exposed during the two months lactation period. Analyses were performed by high resolution gas chromatography. The levels of individual organochlorines varied significantly between tissues; the tissue/blood ratio (on a fat basis) varied by two orders of magnitude for individual congeners. The bioconcentration of the toxic planar PCB-169 congener was the highest in the liver and the lowest in the brain of the sheep.
Descriptors     POLYCHLORINATED BIPHENYLS
HEXACHLOROBENZENE
FUNGICIDES, INDUSTRIAL
DDE
INSECTICIDES, ORGANOCHLORINE
ENVIRONMENTAL POLLUTANTS
ANIMALS, NEWBORN
ANIMALS, SUCKLING
BRAIN
LACTATION
LIVER
SHEEP
TISSUE DISTRIBUTION