Author/Editor     Marušič, Dorjan; Žužek, Saša; Pikelj, Tanja; Možina, Martin
Title     Zastrupitev z etilenglikolom
Translated title     Intoxication with ethylene glycol
Type     članek
Source     In: Bručan A, Gričar M, editors. Urgentna medicina: izbrana poglavja 6. Zbornik 7. mednarodni simpozij o urgentni medicini; 2000 jun 14-17; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year     2000
Volume     str. 447-51
Language     slo
Abstract     Ethylene glycol intoxication is a rare but dangerous type of poisoning. It causes a severe acidosis with high anion and osmolal gaps. Clinical manifestations of the ethylene glycol intoxication can be divided in three phases: the neurological stage with hallucinations, stupor and coma; the second - cardiovascular stage with cardiac failure and the third phase characterised with renal failure due to the acute tubular necrosis. After an aggressive gastric emptying, the main treatment is ethanol, which can be given either orally or intravenously, with supportive measures for all symptoms or diseased organ. A 47-year old man ingested 0,3 I of an unknown alcohol beverage few hours before the admission to our hospital. Although his course was complicated by coma, metabolic acidosis with high anion gap and kidney failure, the patient survived. He was discharged fifteen days later with mild renal failure and anaemia with comlete nor malisation six mounths later at out patient visite. Sustained ethanol intusion and haemodialysis were instituted before obtaining the laboratory confirmation of the ingestion.
Descriptors     ETHYLENE GLYCOLS
MIDDLE AGE
ACIDOSIS
COMA
HEART FAILURE, CONGESTIVE
KIDNEY TUBULAR NECROSIS, ACUTE
HALLUCINATIONS
GASTRIC LAVAGE
HEMODIALYSIS
PYRIDOXINE