Author/Editor		Meh, Duška; Denišlič, Miro
Title		Sensory versus motor evoked potentials in patients with optic neuritis and risk to dvelop multiple sclerosis
Type		članek
Source		In: INABIS 2000. 6th internet world congress for biomedical science; 2000 Feb 14-25; La Mancha; Spain. La Mancha: Spanish society of health informatics,
Publication year		2000
Language		eng
Abstract		In searching for clinical silent lesions of the central nervous system apart from the visual system, in 19 patients with acute isolated optic neuritis, recordings were made of multimodal sensory evoked potentials and central motor latencies using transcranial electrical motor cortex stimulation. None of the patients had symptoms or signs of the involvement of the central nervous system apart from the visual system. Visual evoked potentials were abnormal in all patients, while brainstem acoustic evoked potentials and somatosensory evoked potentials showed abnormalities in 16 % and 11 % of the patients, respectively. Delayed central motor latency occurred in 37 % of the patients. In five years, 32 % of patients with isolated optic neuritis developed clinically definite MS. All these patients had delayed central motor latency. The calculation of central motor latency give a sensitive tool for the prediction of additional central lesions in optic neuritis patients.
Descriptors		OPTIC NEURITIS MULTIPLE SCLEROSIS RISK FACTORS EVOKED POTENTIALS, SOMATOSENSORY CENTRAL NERVOUS SYSTEM DISEASES EVOKED POTENTIALS, VISUAL EVOKED POTENTIALS, AUDITORY, BRAIN STEM DEMYELINATING DISEASES