Author/Editor		Pečovnik-Balon, B; Krpan, D
Title		Patients with analgetic nephropathy on chronic hemodialysis have a high incidence of severe secondary hyperparathyroidism
Type		članek
Source		Clin Nephrol
Vol. and No.		Letnik 50, št. 6
Publication year		1998
Volume		str. 347-51
Language		eng
Abstract		Between 1996 and 1997, 86 patients were treated for terminal renal failure by hemodialysis at Maribor Teaching Hospital. Among them were 12 with iPTH over 900 pg/ml and symptoms of bone disease. In these patients bone biopsy was carried out with the aim of determining the type of renal osteodystrophy (RO) and establishing a possible correlation with the clinical picture, with densitometry and laboratory results. Histomorphologically, 6 patients fulfilled the criteria for secondary hyperparathyroidism (HT) - 3 with analgetic nephropathy (AN), one with chronic pyelonephritis (CPN), one with vascular nephropathy (VN), one with chronic glomerulonephritis (CGN). Six patients fulfilled the criteria for mixed osteodystrophy (MO) - 3 AN, 2 CGN, one VN. According to laboratory findings and bone mineral density (BMD), a statistically significant difference between HT and MO was present only in AP (Table 1). The most frequent diagnosis in patients with iPTH >900 pg/ml was analgetic nephropathy.
Descriptors		ANALGESICS HEMODIALYSIS HYPERPARATHYROIDISM, SECONDARY KIDNEY FAILURE, CHRONIC MIDDLE AGE BONE AND BONES CALCITRIOL CALCIUM PARATHYROID HORMONES RENAL OSTEODYSTROPHY