Author/Editor		Zupan, Igor; Belčijah, Arifi; Kenda, Miran F
Title		Razširjenost dejavnikov ogrožanja za nastanek ateroskleroze pri bolnikih z ugotovljeno koronarno boleznijo srca v ljubljanski in primorski regiji
Translated title		Prevalence of risk factors for atherosclerosis in patients with known coronary heart disease in the Ljubljana and Primorje region
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 69, št. 6
Publication year		2000
Volume		str. 429-34
Language		slo
Abstract		Background. Cardiovascular diseases are serious impediment to normal life and an important cause of premature death. In Slovenia is very similar situation to that in well-developed European countries; ishaemic heart disease as the consequence of coronary atherosclerosis is the prevalent cardiovascular disease. The origins of atherosclerosis are not yet completely understood, but there are identified numerous, partly preventable risk factors precipitating the development of atherosclerosis. The aims of our study were: 1. To detrmine whether risk factors in patients with already known coronary heart disease differ from risk factors in randomly selected people of adult population. 2. To identify the most frequent risk factors for coronary heart disease. 3. To determine difference between sex. In 135 patients with coronary heart disease the following risk factors were studied in detail: Hypertension, hyperlipidemia, cigarette smoking, serum glucose, obesity, lack of physical activity, heredity, alcohol consumption, salt intake, sex and age. Conclusions. Risk factors which depend on lifestyle (obesity, cigarette smoking, salt intake, lack of physical activity, alcohol consumption) were found to be present up to 30% more frequently in patients with coronary heart disease as in compared group. The differences among listed risk factors were statistically significant. Risk factors which can be influenced by drugs (hypertension, hyperlipidemia, serum glucose) were represented equaly in both groups. No significant differences between sex were observed. The starting points for preventive programs are given.
Summary		Izhodišča. Bolezni srca in ožilja zelo otežujejo življenje in povzročajo prezgodnjo smrt. V Sloveniji so razmere podobne kot v razvitih evropskih državah. Največ srčnih bolnikov zajema ishemična bolezen srca, ki nastane zaradi ateroskleroze koronarnega ožilja. Žal še ne vemo natanko, kaj povzroča aterosklerozo, dovolj dobro pa smo seznanjeni s številnimi dejavniki ogrožanja, ki pomembno vplivajo na razvoj ateroskleroze in na katere lahko tudi delno vplivamo. Cilj naše raziskave je bil ugotoviti, ali se dejavniki ogrožanja pri bolnikih z že ugotovljeno koronarno boleznijo kaj razlikujejo od dejavnikov ogrožanja pri naključno izbranih ljudeh. Želeli smo ugotoviti, kateri so najpogostejši dejavniki in kakšne so razlike med njimi glede na spol. V raziskavi so bili pri 135 bolnikih z znano koronarno boleznijo podrobneje analizirani naslednji dejavniki ogrožanja: Zvečani krvni tlak, zvišane maščobe v krvi, kajenje, zvišani krvni sladkor, debelost, fizična neaktivnost, dedna obremenjenost, čezmerno uživanje alkohola, dosoljevanje ter spol in starost. Zaključki. Ugotovitve kažejo, da je navzočnost dejavnikov ogrožanja, ki se nanašajo na življenski slog (debelost, kajenje, velika poraba soli, pomanjkljiva telesna aktivnost in čezmerno uživanje alkohola), do 30% večja kot pri naključnih preiskovancih. Razlike so že statistično pomembne ali pa kažejo visok trend. Pogostnost dejavnikov ogrožanja, na katere lahko vplivamo z zdravili (krvni tlak, holesterol, krvni sladkor), pa je enaka kot pri naključnih preiskovancih. Med spoloma večinoma ni pomembnih razlik. Rezultate naše raziskave moramo upoštevati pri načrtovanju intervencij v primarni in sekundarni preventivi. Podana so izhodišča za preventivne programe.
Descriptors		CORONARY DISEASE ATHEROSCLEROSIS RISK FACTORS SEX FACTORS AGE FACTORS ALCOHOL DRINKING SMOKING HYPERTENSION HYPERLIPIDEMIA OBESITY BLOOD GLUCOSE