Author/Editor		Mičetić-Turk, Dušanka
Title		Novejša spoznanja o etiologiji kronične vnetne črevesne bolezni
Translated title		Recent advances in the etiology of the chronic inflammatory bowel disease
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 39, št. 2
Publication year		2000
Volume		str. 159-67
Language		slo
Abstract		In the article recent advances in the etiology of inflammatory bowel disease, which remain unknown despite intensive research effort, are presented. The role of the mucosal immune system in the mechanismus of inflammatory bowel disease, have been proven although the effector mechanism as well as target cells have not been precisely identified. In the past decade, research was directed particularly toward immunology, genetics and infectology. Numerous microbes are mentioned as possible agents, most frequently Mycobacterium paratuberculosis, measles virus and Listeria monocytogenes. All these studies may have a significant impact on diagnosis and treatment of classical forms of chronic intestinal diseases and their variants.
Summary		V prispevku so prikazana novejša spoznanja o etiologiji kronične vnetne črevesne bolezni, ki ostaja nejasna, kljub intenzivnim raziskavam. Vloga sluzničnega imunskega sistema je v zadnjih letih nesporno dokazana v mehanizmu kronične vnetne črevesne bolezni, čeprav efektorni mehanizmi bolezni, kot tudi ciljne celice še niso popolnoma prepoznani. Raziskave so v zadnjem desetletju usmerjene predvsem na imunologijo, genetiko in infektologijo. Kot možne povzročitelje navajajo številne mikrobe, med katerimi so najpogostejši Mycobacterium paratuberculosis, virus ošpic in Listeria monocytogenes. Vse te raziskave lahko bistveno vplivajo na diagnostiko in zdravljenje klasičnih oblik kroničnih vnetnih črevesnih bolezni in njihovih različic.
Descriptors		INFLAMMATORY BOWEL DISEASES MYCOBACTERIUM PARATUBERCULOSIS LISTERIA MONOCYTOGENES MEASLES VIRUS INTESTINAL MUCOSA DIET