Author/Editor		Grčevska, L; Polenaković, M
Title		"Garland" pattern post-streptococcal glomerulonephritis - clinical characteristics and long-term follow-up
Type		članek
Source		In: Lindič J, Kaplan-Pavlovčič S, editors. Zbornik prispevkov 1. slovenski nefrološki kongres z mednarodno udeležbo; 1996 okt 23-26; Portorož. Ljubljana: Klinični center, Nefrološka klinika,
Publication year		2000
Volume		str. 22-7
Language		eng
Abstract		"Garland" pattern of PSGN is characterized with densely packed and sometimes confluent deposits on immunofluorescence, located in the region of capillary walls. Subepithelial "humps", seen on electron microscopy are confluent subendothelial, intramembranous and mesangial deposits are much less prominent. Higher degree of proteinuria and unfavorable long-term follow-up were described. We present 13 patients with "garland" pattern PSGN and correlate their clinical features at biopsy and prognosis with the other patterns: "starry sky" 20 cases and "mesangial" form 24 cases. Differences in age of patients and severity of hypertension at biopsy were not significant. Incidence of acute renal failure was high in "garland" pattern PSGN, it was noted in 1 1/13 (84.6%) of the patients. "Garland" pattern cases presented significantly higher values of creatinine correlated with "starry sky" p=0.009 and mesangial pattern p = 0.039. Serum levels of creatinine for "garland" pattern patients were 87-1602 micromol, (M +- SD) 315 +- 405. "Garland" pattern patients presented also significantly higher degree of proteinuria correlating with "starry sky" pattern p = 0.008. Proteinuria in "garland" pattern cases ranged between 0.21 and 27 g/L, (M +- SD) 9.03 +- 9.09. Patients were followed 2-12 years and "garland" pattern patients did not developed chronic renal failure during followup. Clinical features noted during followup were erythruria with a duration M +- SD 23 +- 14 months and proteinuria 25 +- 11 months. (Abstract truncated at 2000 characters.)
Descriptors		GLOMERULONEPHRITIS STREPTOCOCCAL INFECTIONS IMMUNE COMPLEX DISEASES PROTEINURIA BIOPSY HYPERTENSION MICROSCOPY, ELECTRON FLUORESCENT ANTIBODY TECHNIQUE FOLLOW-UP STUDIES HEMATURIA PROGNOSIS