Author/Editor		Meglič, A; Čavič, M; Hren-Vencelj, H; Tršinar, B; Ravnik, M
Title		Klamidijska okužba sečil pri otrocih in mladostnikih z izolirano mikrohematurijo
Type		članek
Source		In: Lindič J, Kaplan-Pavlovčič S, editors. Zbornik prispevkov 1. slovenski nefrološki kongres z mednarodno udeležbo; 1996 okt 23-26; Portorož. Ljubljana: Klinični center, Nefrološka klinika,
Publication year		2000
Volume		str. 152-6
Language		slo
Abstract		Urogenital chlamydial infection in adults and adolescents is a common, sexually transmitted disease, while in prepubertal children it has not been thoroughly investigated yet. In our clinical practise we had observed several cases of isolated microhaematauria in children with urogenital chlamydial infection. Therefore we designed a study to compare the incidence of chlamydial infection in 37 children and adolescents with isolated microhaematuria in the study group versus the incidence in the 37 matched controls without haematuria. The infection was confirmed by isolating Chlamydia trachomatais in cell culture from the urethral smear, by direct immunofluorescence (DIF) test and enzyme immunoassay (EIA) to demonstrate chlamydial antigene in urine, and by polimerase chain reaction (PCR) to demonstrate chlamydial DNA in urine. Chlamydial infection was found to be significantly more frequent in the study group (8/37) as compared to the controls (0/37) (p = 0.0026). The infected patients were 5 to 12 years old (average 9.0 +- 2.3 years). The infection was confirmed with isolation of Chlamydia in 6 patients and with DIF in urine in 2 patients respectively. Infected patients were free of symptoms, suggestive of chlamydial infection, however, inflammatory changes of the urethra detected by cystourethroscopy were significant more frequent in those with chlamydial infection than in those with haematuria without infection (37.55% vs 3.4%). We concluded that chlamydial infection can be associated with isolated microhaematuria. Morning urine sample for DIF test was found as a very reliable method to replace isolating Chlamydia in cell culture from the urethral smear.
Descriptors		URINARY TRACT INFECTIONS CHLAMYDIA TRACHOMATIS HEMATURIA CHILD ADOLESCENCE