Author/Editor     Glavaš-Boras, S; Puretić, Z; Slaviček, J; Kalenić, S; Boras, S; Bubić-Filipi, Lj; Šmalcelj, R; Pasini, J; Mareković, Z
Title     Efficacy of exit site/tunnel Staphylococcus aureus infection treatment with oral pefloxacin and rifampicin
Type     članek
Source     In: Lindič J, Kaplan-Pavlovčič S, editors. Zbornik prispevkov 1. slovenski nefrološki kongres z mednarodno udeležbo; 1996 okt 23-26; Portorož. Ljubljana: Klinični center, Nefrološka klinika,
Publication year     2000
Volume     str. 248-50
Language     eng
Abstract     Continuous ambulatory peritoneal dialysis (CAPD) can be compromised by infections of the skin and subcutaneous tunnel around the peritoneal catheter. Over the period 1983 - 1996 (4.892 dialysis months) 141 adult patients were treated with CAPD. Inflammations of the skin and of the subcutaneous tunnel occurred on 26 occasions. Out of these 26, 19 were treated conservatively. In 3 cases, having occurred up to 1988, apart from conservative therapy, peritoneal catheter was removed (2 of these peritonitides were caused by S. aureus and 1 by S. epidermidis). Infections were caused by S. aureus (14/ 26), S. epidermidis (6/26), E. Coli (4/26), P aeruginosa (2/26). Since 1988 the 14 S. aureus infections have been treated conservatively, with oral pefloxacin (800 mg on the 1 st day, and then 400 mg/day) and rifampicin (600 mg/day) for 1 month. The skin around the catheter was cleansed daily with povidone-iodide. The infected area was covered with sterile gauze dressings. In this way 8/14 cases of S. aureus infection were cured, with no recurrences within the following 6-month period.
Descriptors     PERITONEAL DIALYSIS, CONTINUOUS AMBULATORY
SKIN DISEASES, BACTERIAL
STAPHYLOCOCCUS AUREUS
PEFLOXACIN
RIFAMPIN