| Author/Editor | Boh, M; Ponikvar, R; Buturović-Ponikvar, J; Kveder, R | |
| Title | Factor assocated with nutritional status in hemodialysis patients | |
| Type | članek | |
| Source | In: Lindič J, Kaplan-Pavlovčič S, editors. Zbornik prispevkov 1. slovenski nefrološki kongres z mednarodno udeležbo; 1996 okt 23-26; Portorož. Ljubljana: Klinični center, Nefrološka klinika, | |
| Publication year | 2000 | |
| Volume | str. 271-7 | |
| Language | eng | |
| Abstract | In order to identify the association between protein-energy malnutrition (PEM) and some potentially influential factors we evaluated the nutritional status (NS) in a crossectional study in 157 patients on chronic hemodialysis. Composite nutritional index (CNI) was used to determine NS. The impacts of dialyser membrane type, acid-base status, dialysis dose and dietary protein intake (DPI) on NS were studied. We tested the hypothesis that the use of bioincompatible dialysers, metabolic acidosis, inadequate dialysis dose and insufficient DPI contribute significantly to PEM. Overt malnutrition (CNI score >= 11) was present in 25 patients (16%). Thirty seven patients (24%) showed no signs of PEM (CNI score = 0). There was no significant link between NS and dialyser membrane type or serum bicarbonate level. We used the KW urea as an index of dialysis dose. The protein catabolic rate (nPCR) was used to assess DPI. Regression analysis of the two variables was not statistically significant. The mean value (M+-SD) of KT/V urea was 1.33+-0.5. The mean value of nPCR was 0.95+-0.22 (g/kg of body weight/day). Kt/V and nPCR values, normalised to ideal body weight, were significantly lower in the group of malnourished patients (p<0.0007) compared with patients without signs of PEM. The dialysis treatment period was longer in malnourished patients (p=0.02). Conclusions: Our results indicate that inadequate DPI is an important factor in the etiology of PEM but it is not related to dialysis dose. DPI in our patients is in general insufficient. There is no associa tion between metabolic acidosis or the use of bioincompatible dialysers and clinical signs of PEM. | |
| Descriptors | KIDNEY FAILURE, CHRONIC PROTEIN-ENERGY MALNUTRITION NUTRITIONAL STATUS HEMODIALYSIS HEMODIALYSIS SOLUTIONS UREA BICARBONATES HYDROGEN-ION CONCENTRATION CREATININE BLOOD PROTEINS |