Author/Editor		Buturović-Ponikvar, J; Urbančič, A; Kandus, A; Ponikvar, R; Bren, AF; Novljan, G; Kenda, R
Title		Renal transplant artery stenosis in pediatric transplantation
Type		članek
Source		In: Buturović-Ponikvar J, Bren AF, editors. Zbornik 2. slovenski nefrološki kongres z mednarodno udeležbo ob 30. letnici dialize in transplantacije ledvic v Sloveniji; 2000 sep 27-30; Brdo pri Kranju. Ljubljana: Klinični center, Klinični oddelek za nefrologijo,
Publication year		2000
Volume		str. 61-6
Language		eng
Abstract		The aim of our study was to assess the influence of renal transplant artery stenosis on graft function and hypertension in children. 12 renal transplantations were performed in 11 children (from 1994-1999), aged from 7-17 years 5 from living related and 7 from cadaveric donor. Stenoses were established by duplex-Doppler examinations using previously established criteria (intrastenotic peak systolic velocity >2 m/s on at least two independent measurements). Angiography was performed in the cases with positive Doppler and deteriorating renal function (3/5). In 5/12 transplants significant stenosis (50-75%) was found by duplex-Doppler in the first two weeks after transplantation, 3 located at the anastomosis and one 2 cm distally from the anastomosis, towards hilus. 2/5 stenosis were corrected, one surgically and one by percutaneous transluminal dilatation, and in both case significant residual stenosis remained. No graft was lost because of stenosis. We found no progression of stenosis (both treated and untreated) during regular duplex-Doppler follow-up up to 3 years after transplantation. In one case stenosis was no detectable after 6 months. There was no significant difference in serum creatinine at 1 year, number of antihypertensive drugs and number of rejection comparing patients with and without stenosis. According to our experience renal transplant artery stenosis in pediatric renal trans plantation tends to be stable over time and does not require aggressive treatment in cases with stable renal function. Spontaneous remission is possible.
Descriptors		KIDNEY TRANSPLANTATION RENAL ARTERY OBSTRUCTION CHILD HYPERTENSION ULTRASONOGRAPHY, DOPPLER, DUPLEX