Author/Editor | Prelog, I; Krajnc, I; Lukanovič, K | |
Title | Treatment of psoriatic arthritis with cyclosporin A | |
Type | članek | |
Source | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. and No. | Letnik 9, št. 3 | |
Publication year | 2000 | |
Volume | str. 110-2 | |
Language | eng | |
Abstract | The purpose of this study was to determine the efficacy and toxicity of cyclosporin A (CsA) in treatment of patients affected with psoriatic arthritis (PsA). Methods: This study includes 11 patients with PsA. Clinical and functional parameters are assessed: Ritchie Index, duration of the morning stiffness of joints in minutes, and pain. Laboratory values in serum were checked: SR, CRP, urea, creatinin, cholesterol, trigliceride, electrolyte, and liver enzymes. Measurements of blood pressure were taken monthly. Results: With a therapeutic dose of CsA 3 mg/kg/daily we noticed an improvement of clinical parameters, but not of laboratory values. Conclusion: The investigation showed that CsA in the dosis of 3 mg/kg/daily was efficient and safe in the treatment of PsA. | |
Descriptors | ARTHRITIS, PSORIATIC CYCLOSPORINE TREATMENT OUTCOME |