Author/Editor     Korsika-Mrak, J; Vizjak, A; Penko, M; Kansky, A
Title     IgA linear bullous dermatosis. A case report
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 9, št. 3
Publication year     2000
Volume     str. 113-7
Language     eng
Abstract     A case of linear IgA dermatosis in a 71-year-old female patient is reported. She was previously treated with enalapril for arterial hypertension in the course of several years. At the last admission she mentioned that oral lesions have been appearing periodically, blister have been noticed about 2 months before. Histopathology revealed a subepidermal blister, and direct immunofluorescence disclosed linear IgA as well as granular C3 deposits along the epidermal basement membrane. The treatment with methylprednisolon starting with a dosis of 125 mg i.m. was successful. Additionally, dapsone was applied in a dosis of 100 mg daily, but it had to be discontinued because of methemoglobinemia. The dosis of methylprednisolon was gradually decreased and she left the hospital with 32 mg daily.
Descriptors     SKIN DISEASES, VESICULOBULLOUS
IGA
BLISTER
MICROSCOPY, FLUORESCENCE
METHYLPREDNISOLONE
DAPSONE
AGED