Author/Editor | Korsika-Mrak, J; Vizjak, A; Penko, M; Kansky, A | |
Title | IgA linear bullous dermatosis. A case report | |
Type | članek | |
Source | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. and No. | Letnik 9, št. 3 | |
Publication year | 2000 | |
Volume | str. 113-7 | |
Language | eng | |
Abstract | A case of linear IgA dermatosis in a 71-year-old female patient is reported. She was previously treated with enalapril for arterial hypertension in the course of several years. At the last admission she mentioned that oral lesions have been appearing periodically, blister have been noticed about 2 months before. Histopathology revealed a subepidermal blister, and direct immunofluorescence disclosed linear IgA as well as granular C3 deposits along the epidermal basement membrane. The treatment with methylprednisolon starting with a dosis of 125 mg i.m. was successful. Additionally, dapsone was applied in a dosis of 100 mg daily, but it had to be discontinued because of methemoglobinemia. The dosis of methylprednisolon was gradually decreased and she left the hospital with 32 mg daily. | |
Descriptors | SKIN DISEASES, VESICULOBULLOUS IGA BLISTER MICROSCOPY, FLUORESCENCE METHYLPREDNISOLONE DAPSONE AGED |