Author/Editor     Furlan, Borut; Kocjan, Darko; Grahek, Rok; Uštar, Matjaž; Žmitek, Janko
Title     Raziskava profila in izvora nečistoč v amlodipinu benzensulfonatu
Type     članek
Source     In: Glavič P, Brodnjak-Vončina D, editors. Zbornik referatov s posvetovanja Slovenski kemijski dnevi 2000: 1. in 2. del; 2000 sep 28-29; Maribor. Maribor: FKKT,
Publication year     2000
Volume     str. 119-24
Language     slo
Abstract     Impurity profile of the amlodipine benzenesulfonate prepared from trityl-amlodipine was investigated. Knowing the identity and origin of the impurities the technology for the synthesis was optimized affording the active compound of high purity. For this purpose influences on the trans-esterification of amlodipine benzenesulfonate was particularly investigated.
Descriptors     AMLODIPINE
BENZENESULFONATES
DRUG CONTAMINATION
DRUG INDUSTRY
CHEMISTRY, PHARMACEUTICAL