Author/Editor		Poredoš, Pavel; Šabovič, Mišo
Title		Strokovne podlage za razvrščanje zdravil glede na učinkovitost
Translated title		Classification of the drugs according to their efficacy
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 69, št. Suppl 1
Publication year		2000
Volume		str. I-15-7
Language		slo
Abstract		Background. There are approximately 2940 drugs registered in Slovenia. Since the amount of funds that are earmarked for medical treatment by drugs is limited, a rational and technically supported distribution of these funds is necessary. One important step towards this aim would be a classification of drugs according to their efficiency. For this classification references are suggested, which are based on the methods of results in basic medicine. This enables the most objective evaluation of the drug-efficiency. The classification should be divided into three levels: the definition of drugs that are not efficacious; the division of drugs to "symptomatic" drugs and drugs that influence "important" clinical results and the arrangement of drugs in this last group into an efficiency-scale. It would be reasonable if each of the medical lines would prepare that kind of the classification for those drugs, which are used in its field. The quantity of appropriate information on the drug-efficiency has increased considerably in the last few years. None the less the main problem for the suggested classification at the moment present a relative lack of appropriate information and a lot of inappropriate represented and interpreted information. In spite of all that we can already lay foundations of a surveyable and objective system for the classification of drugs according to their efficiency. In the future the system can be upgraded and improved by collecting new information. While distributing funds for drugs, not only the drug-efficiency, but pharmaco-economical analyses which have to be based on results in basic medicine should be considered.
Summary		Izhodišča. V Sloveniji je registrirano približno 2940 zdravil. Ker je količina sredstev, ki je namenjena za zdravljenje z zdravili, omejena, je nujno racionalno in strokovno podprto razdeljevanje sredstev za zdravila. Eden izmed pomembnih korakov k temu cilju bi bila razvrstitev zdravil glede na njihovo učinkovitost. Zaključki. Predlagamo priporočila za razvrščanje zdravil, ki imajo za osnovo metode na izsledkih temelječe medicine. Ta omogoča najbolj objektivno oceno učinkovitosti zdravila. Razvrščanje naj bi potekalo na treh ravneh: določitev zdravil, ki niso učinkovita; razdelitev zdravil na "simptomatska" zdravila in zdravila, ki vplivajo na "pomembne" klinične izvide, ter razvrstitev zdravil iz zadnje skupine v učinkovitostno lestvico. Smiselno bi bilo, da bi vsaka medicinska stroka za zdravila, ki se uporabljajo na njenem področju, pripravila takšno razvrstitev. Količina ustreznih podatkov o učinkovitosti zdravil v zadnjih letih strmo narašča. Kljub temu pa je za sedaj glavna težava za predlagano razvrstitev relativno pomanjkanje primernih podatkov in dodatno še številni neustrezno prikazani ali tolmačeni podatki. Kljub temu lahko že sedaj postavimo temelje za pregleden in objektiven sistem za razvrščanje zdravil po učinkovitosti. v bodočnosti bomo s pridobivanjem novih podatkov sistem lahko dopolnjevali in izboljševali. Pri razdeljevanju sredstev za zdravila je seveda potrebno poleg učinkovitosti zdravil upoštevati predvsem farmakoekonomske analize, ki morajo prav tako temeljiti na metodah na izsledkih temelječe medicine.
Descriptors		PRESCRIPTIONS, DRUG DRUG UTILIZATION INSURANCE, HEALTH EVIDENCE-BASED MEDICINE SLOVENIA