Author/Editor		Žvan, Bojana
Title		Tveganje za ishemično možgansko kap pri atrijski fibrilaciji
Translated title		Stroke risk in atrial fibrillation
Type		članek
Source		In: Kenda MF, Rakovec P, editors. Sodobna obravnava motenj srčnega ritma. 9. kardiološki dnevi; 2000 okt 20-21; Šmarješke toplice. Ljubljana: Združenje kardiologov Slovenije,
Publication year		2000
Volume		str. 151-5
Language		slo
Abstract		The most clinically relevant advance in the management of cardiac arrhythmias in the past two decades has been that anticoagulant treatment substantially reduced the risk of stroke in patients with atrial fibrillation. The fact that each year 4-5 % of patients with atrial fibrillation will have a stroke prompted several randomized trials of treatment with anticoagulants that reported a reduction in the incidence of strokes with warfarin. A meta-analysis of these trials shows that the risk is reduced by two thirds. Major risk factors for stroke are age over 75, previous stroke or transient ischemic attack, arterial hypertension, diabetes mellitus, mitral stenosis, dilative cardiac disease, and left ventricular dysfunction. Patients with atrial fibrillation and any of these risk factors face a higher than average risk (5-15 % per year) of a stroke. On the other hand, the risk of a stroke in patients with none of these risk factors is too low for warfarin to be beneficial. The recommended anticoagulant treatment should aim to keep the international normalized ratio between 2,0 and 3,0. These guidelines of anticoagulation in patients with atrial fibrillation are recommended to all Slovenian physicians.
Descriptors		ATRIAL FIBRILLATION CEREBRAL EMBOLISM AND THROMBOSIS CEREBROVASCULAR DISORDERS RISK FACTORS ANTICOAGULANTS