Author/Editor		Majcen-Vivod, Božislava; Urlep-Šalinovič, Vera; Jelatancev, Biserka
Title		Prenos hepatitisov B in C s krvjo v SB Maribor v triletnem obdobju od 1996 do 1998
Translated title		Transmission of hepatitis B and C by blood at the Maribor teaching hospital in the period from 1996 to 1998
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 39, št. Suppl 5
Publication year		2000
Volume		str. 3-8
Language		slo
Abstract		Background. The article deals with the risk of transmission of hepatitis B and C virus by blood transfusion. At the Maribor Teaching Hospital we have 13,000 donations per year. We also test blood from patients for hepatitis B and C. Methods. We found the data about patients in the Datec computer program which is used at the transfusion center and other institutions in Slovenia. Results. In a three-year period we tested 15116 persons for HBsAg and 214 of them were positive (1.41%). Three first time HBsAg positive persons were also treated with blood products. We found frozen samples from these donors and tested HBsAg and anti-HBc antibodies again. The results were negative. Among 8081 persons tested for HCV antibodies 166 were positive (2.05%). Eleven persons with HCV antibodies were treated with blood. Three positive persons received blood before blood donor testing was introduced in 1993. We found transmission in one case. Eight persons were treated with HCV negative blood. Conclusion. We did not find any transmission of hepatitis B and C in the window period after blood donor testing for antibodies to hepatitis C was started in 1993.
Summary		Izhodišča. V retrospektivni raziskavi smo želeli ugotoviti tveganje za prenos hepatitisov B in C s krvjo v SB Maribor, kljub rutinskemu testiranju krvi. V SB Maribor imamo letno približno 13.000-14.000 odvzemov krvi, testiramo pa tudi bolnike na povzročitelje hepatitisov B in C. Material in metode. Podatke o bolnikih smo poiskali iz računalniškega programa DATEC, ki ga uporabljamo na transfuzijskih oddelkih po Sloveniji. Rezultati. V triletnem obdobju smo med 15116 preiskovanci odkrili 214 oseb s pozitivnim HBsAg (1,41 %). Med 214 novo odkritimi pozitivnimi osebami so bile 3 zdravljene s krvjo. Rezultati ponovnega testiranja hranjenih vzorcev krvi krvodajalcev na HBsAg in anti-HBc-protitelo so bili negativni. Med 8.081 preiskovanci na protitelesa proti hepatitisu C smo ugotovili 166 oseb s protitelesi proti hepatitisu C (2,05 %). Med 166 novo odkritimi pozitivnimi osebami smo odkrili 11 oseb, zdravljenih s krvjo. Tri osebe s prisotnimi protitelesi proti hepatitisu C so dobivale kri že pred uvedbo obveznega testiranja na označevalce hepatitisa C in v enem primeru je prišlo do prenosa. Osem bolnikov je bilo zdravljenih s HCV-negativno krvjo po uvedbi testiranja. Zaključek. V omenjeni raziskavi nismo odkrili prenosa okužbe z virusom hepatitisa B in C zaradi napake pri testiranju ob odvzemu krvi v obdobju diagnostičnega okna po uvedbi testiranja protiteles na hepatitis C leta 1993.
Descriptors		BLOOD TRANSFUSION BLOOD DONORS DISEASE TRANSMISSION HEPATITIS B HEPATITIS C HEPATITIS B SURFACE ANTIGENS HEPATITIS B ANTIBODIES HEPATITIS C ANTIBODIES