Author/Editor		Kovačič, Dragan
Title		Pomen dejavnikov strjevanja krvi za nastanek globoke venske tromboze
Translated title		Role of coagulation factors in the development of deep venous thrombosis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 39, št. Suppl 5
Publication year		2000
Volume		str. 185-8
Language		slo
Abstract		Deep venous thrombosis (DVT) is a partial or total obstruction of the deep venous system by a thrombus. We divide the risk factors for development of DVT into congenital, acquired and combined. Today we can determine the causes of DVT in around 80% of patients using the methods that are available at present. The article focuses on coagulation factors as a limited subbgroup of congenital and combined risk factors for the development of DVT. It tries to estimate the individual contributions of the coagulation factors to the total risk for development of DVT on the basis of information in the literature. The goal of the article is to improve the knowledge thrombophilia. It should facilitate recognition of certain risk groups and in the final phase lead to modified therapeutical and preventive approaches that are more suitable to the risk groups.
Summary		Globoka venska tromboza (GVT) je delna ali popolna zamašitev globokega venskega sistema s strdkom. Dejavnike tveganja za nastanek GVT delimo na prirojene, pridobljene in mešane. Vzrok za nastanek uspemo z danes razpoložiljivimi metodami najti pri okoli 80 % bolnikov (3). Prispevek se osredotoča na dejavnike strjevanja kot omejeno podskupino prirojenih in mešanih dejavnikov tveganja za razvoj GVT. Skuša tudi opredeliti individualne prispevke posameznih dejavnikov k skupnemu tveganju za razvoj GVT glede na podatke, ki obstajajo v literaturi. Cilj prispevka je izboljšati poznavanje trombofilije, s tem pa tudi olajšati prepoznavanje rizičnih skupin, kar naj bi v končni fazi vodilo v rizičnim skupinam bolj prilagojene terapevtske oz. profilaktične ukrepe.
Descriptors		THROMBOPHLEBITIS BLOOD COAGULATION DISORDERS RISK FACTORS BLOOD COAGULATION FACTORS