Author/Editor		Jarm, T; Wickramasinghe, YABD; Deakin, M; Čemažar, M; Elder, J; Rolfe, P; Serša, G; Miklavčič, D
Title		Blood perfusion of subcutaneous tumours in mice following the application of low-level direct electric current
Type		članek
Source		Adv Exp Med Biol
Vol. and No.		Letnik 471
Publication year		1999
Volume		str. 497-506
Language		eng
Abstract		Electrotherapy with low-level direct electric current has been proved to be an effective local treatment of solid tumours. In the presented study an attempt was made to evaluate the effect of a single treatment with electro therapy on blood perfusion of solid subcutaneous fibrosarcoma Sa-1 tumours in A/J mice. The tissue-standing method with Patent blue-violet dye, the rubidium extraction technique, and the noninvasive nearinfrared spectroscopy method were used for this purpose. Results of all methods indicate that perfusion and subsequently oxygenation of tumours were reduced due to application of electrotherapy.
Descriptors		SARCOMA, EXPERIMENTAL ELECTRIC STIMULATION THERAPY RUBIDIUM SPECTROSCOPY, NEAR-INFRARED