Author/Editor		Butinar, Dušan; Žgur, Tomaž
Title		Kaj je epilepsija?
Type		članek
Source		In: Dšuban G, Šilc T, Vodušek DB, et al, editors. Simpozij Ocenjevanje invalidnosti, telesne okvare in potrebe po pomoči in postrežbi drugega pri nevroloških bolnikih; 2000 dec 8-9; Ljubljana. Ljubljana: Zavod za pokojninsko in invalidsko zavarovanje Slovenije, Invalidska komisija 2. stopnje,
Publication year		2000
Volume		str. 51-8
Language		slo
Abstract		Epilepsy is transient, sudden, reversible and reccurent neurologic disturbance which is due to transient paroxysms of excesive discharges of neurons. Pathopysiologic basis of these discharges are paroxysmal depolarisation shifts of membrane potential of neurons in epileptic focus which results from ion channel disfunction. In seazure, abnortnal excitatory and inhibitory influences result in sinchro- nisation and spreading of excesive activity. The aetiology of epilepsy is multifactorial - resutting from genetic and acquired factors. Dynamic interaction between the seazure threshold and seazure precipitants determine an individual's propensity to develop seazure and chronic epilepsy. Epilepsy is a very common condition with the incidence up to 100/100000 and a cumulative incidence between 2 an 5 %. Epilepsy is classified according to underlying aetiology into symptomatic, idiopatic and cryptogenic, and according to localisation into partial, generalised, undetermined and special syndromes. The prognosis for seazure control is quite good - 70 to 80 % of people with epilepsy will become seazure-free, and about half of them will be able to withdraw their medication. 20 to 30 % of patients will develop chronic epilepsy with 5 % of patients having in- tractable epilepsy who are wholy dependant for their day-to-day needs.
Descriptors		EPILEPSY EPILEPSY, GENERALIZED