Author/Editor		Barbara, John
Title		Risk reduction: how to reconcile with epidemiology?
Type		članek
Source		In: Zagotavljanje varnosti. 3. podiplomski seminar Zdravljenje s krvjo v kirurgiji; 2000 dec 14-16; Portorož. Ljubljana: Klinični center - SPS kirurška služba,
Publication year		2000
Volume		str. 9-14
Language		eng
Abstract		Throughout Europe the prevalence and incidence of the various agents that are potentially transmissible by blood transfusion can vary from country and there may be significant differences even within a single country. Before one can decide on the value and appropriateness of extra testing for a given marker, the following information needs to be obtained, checked for accuracy, collated nationally and compared throughout Europe: 1. Prevalence of confirmed positivity rates for the markers of transfusion-transmissible infections (TTIs). 2. Carefully evaluated rates of seroconversion to provide data on incidence of these infections in blood donors. 3. Mean inter-donation intervals for regular blood donors. 4. Proportion of new and repeat donors (using agreed definitions within Europe). 5. Calculations of residual risk of the various infections per donation due to "window-period" infectivity can then be made. 6. Investigation of reported cases of transfusion-associated infections, and collation of the data.
Descriptors		BLOOD TRANSFUSION BLOOD DONORS DISEASE TRANSMISSION INFECTION CONTROL RISK ASSESSMENT COMMUNICABLE DISEASES HIV INFECTIONS HEPATITIS B HEPATITIS B SURFACE ANTIGENS CREUTZFELDT-JAKOB SYNDROME