Author/Editor		Tomšič, Martin; Bajrović, Fajko
Title		Electrically conductive and ferromagnetic nerve guide hinders regeneration of rat's sensory axons. Preliminary report
Type		članek
Source		In: Jarm T, Kotnik T, Miklavčič D, editors. Proceedings including program of the 3rd international conference on bioelectromagnetism and 1st Slovenian-Croatian meeting on biomedical engineering in connection with COST 244bis 11th workshop on biomedical applications of electromagnetic fields and management commitee meeting; 2000 oct 8-12; Bled. Ljubljana: Faculty of electrical engineering,
Publication year		2000
Volume		str. 193-4
Language		eng
Abstract		Electromagnetic fields has been shown to affect neurite outgrowth in experiments in vitro and in vivo. In the present study, the regeneration of sensory axons through electrically conductive and ferromagnetic nerve guides made of stainless steel was evaluated and compared to nerve guides made of silicone rubber. Regeneration of rat's sensory axons into the distal stump of sural nerve was examined 6 weeks after surgery using electrophysiology and histomorphometry. Stainless steel tubes contained nerves with significantly less myelinated and nonmyelinated axons than silicone rubber tubes. It seems that regeneration of injured axons through electrically conductive and ferromagnetic nerve guide is hindered. The hypothesis that axonal outgrowth in vivo is influenced by the electromagnetic field is strongly supported.
Descriptors		SURAL NERVE NERVE REGENERATION NEURONS, AFFERENT ELECTROMAGNETIC FIELDS RATS, WISTAR MYELIN SHEATH