Author/Editor     Kamenik, Mirt
Title     Prilagoditev obtočil na subarahnoidno blokado: vpliv infuzije Reingerjeve raztopine
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     2001
Volume     str. 77
Language     slo
Abstract     Hypotension, the most common side effect of spinal anesthesia, is treated with fluids and vasopressors. Data in the literature about the effectiveness of a crystalloid solution infusion before spinal anesthesia in preventing hypotension after spinal anesthesia are inconclusive. The influence of a crystalloid solution infusion on cardiac output (CO) changes after spinal anesthesia remains unknown. The aim of our study was to evaluate the effects of Ringers solutions infusion, infused either before or immediately after spinal anesthesia, on the time course of blood pressure, CO and peripheral resistance (PR) changes after spinal anesthesia. The hypothesis of our study was that the volume effect of Ringers solution infusion is most effectively used if the infusion is started immediately after spinal anesthesia. We studied 75 patients scheduled for lower extremity surgery under spinal anesthesia. We measured CO and blood pressure for 25 min. before and 30 min. after spinal anesthesia. Patients were randomly to three groups. In the first group ("No infusion" group) no infusion was given during the period of measurements. The second group ("Infusion before the block" group) received 12 ml/kg BW of Ringers solution within 20 minutes before spinal anesthesia. The third group ("Infusion after the block" group) received 12 ml/kg BW of Ringers solution within 20 minutes starting immediately after spinal anesthesia. In the "No infusion" group after spinal anesthesia CO decreased for an average 13.9%, mean arterial pressure (MAP) decreased for an average 6.4 mmHg and PR did not change. In the "Infusion before the block" group, after the infusion and before spinal anesthesia, CO increased for an average 20%, PR decreased for an average 11% and MAP did not change. (Abstract truncated at 2000 characters.)
Descriptors     SUBARACHNOID SPACE
INFUSIONS, PARENTERAL
BLOOD PRESSURE
VASCULAR RESISTANCE
ANESTHESIA, SPINAL
HYPOTENSION
CARDIAC OUTPUT