Author/Editor     Zadravec, Darko; Kerč, Janez; Kristl, Julijana
Title     Pregled gastrointestinalnih pospeševalcev absorpcije učinkovin
Translated title     Review of gastrointestinal drug absorption enchancers
Type     članek
Source     Farm Vestn
Vol. and No.     Letnik 51, št. 4
Publication year     2000
Volume     str. 535-46
Language     slo
Abstract     In introduction absorption mechanisms in digestive tract are shortly presented, followed by review of gastrointestinal absorption enhancers used for peroral drug delivery, their status and the cited tested drugs. The information presented enables reliable choice of approproate absorption enhancers in combination with selected drug substance and pharmaceutical form.
Summary     V prispevku so uvodoma predstavljeni mehanizmi absorpcije v prebavnem traktu, v nadaljevanju je podan pregled gastrointestinalnih pospeševalcev absorpcije uporabljanih pri peroralnem dajanju zdravilnih učinkovin in njihov status, navedene pa so tudi učinkovine, ki so bile z njimi testirane. Članek omogoča lažjo izbiro najučinkovitejšega pospeševalca absorpcije glede na izbrano učinkovino in farmacevtsko obliko.
Descriptors     GASTROINTESTINAL SYSTEM
INTESTINAL ABSORPTION
GLYCERIDES
FATTY ACIDS
CELL MEMBRANE PERMEABILITY
MEMBRANE FLUIDITY
BILE ACIDS AND SALTS
SURFACE-ACTIVE AGENTS
CHELATING AGENTS