Author/Editor		Remškar, Z
Title		Zgodnje odkrivanje azbestoze in objektivno določanje stopnje delazmožnosti prizadetih bolnikov
Translated title		Early detection of asbestosis and determination of the degree of working ability of the affected patients
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1990
Volume		str. 127
Language		slo
Abstract		The problematics in the study is dealing with is an analysis of diagnostic procedures for early detection of asbestosis together with the methods for objective evaluation of working ability of patients involved. The study was performed in the sample of 105 patients in whom the diagnosis had been confirmed at the Institute Golnik mostly during the years 1980-1988. After confirmation of diagnosis of lung/or pleural asbestosis their state of health had been followed for 4,9 yrs (+_3,36). The diagnostic value of case history, clinical examination, chest roentgenogram, lung function tests, basic biochemical blood and urine test as well as immunological examinations, cytologic findings of BAL and histological bronchoscopy had been analysed. The results of the study revealed that basic diagnostic procedures for the diagnosis of asbestosis are case history, clinical examination, chest roentgenogram and spirometry. These diagnostic procedures enable the establishment of diagnosis, evaluation of functional pulmonary impairment and follow-up after the diagnosis had been established in professionaly exposed patients. Only in the absence of typical roentgenological involvement of the lung in professionaly exposed patients with evident clinical symptoms of disease, the diagnostic procedures should be expanded to the histological examination of lung tissue. The transbronchial biopsy of the lung during fiberbronchoscopy has the priority in order to avoid the complications after the intervention. The analysis confirmed the chronic, slowly progressing nature of asbestosis in which pathogenes is - according to our investigations - the alveolar macrophage, provoked by asbestos, has the central role.(trunc.)
Descriptors		ASBESTOSIS OCCUPATIONAL DISEASES DISABILITY EVALUATION LUNG DISEASES PLEURAL DISEASES MEDICAL HISTORY TAKING THORACIC RADIOGRAPHY RESPIRATORY FUNCTION TESTS SMOKING BLOOD CHEMICAL ANALYSIS BRONCHOALVEOLAR LAVAGE FLUID DYSPNEA HYPERTENSION, PULMONARY ASBESTOS