Author/Editor     Starc, R
Title     Maksimalni volumski pospešek kot indeks kontraktilnosti levega ventrikla
Translated title     Maximal volume acceleration as an index of left ventricular contractility
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     1990
Volume     str. 145
Language     slo
Abstract     The measurement of contractility of the left ventricle is of great imporance in cardiology for the assessment of systolic LV function. For this purpose many indices of contractility (indices of pre-ejection and ejection period) have been constructed. It was found by electro-magnetic flow meter (EMFM) that peak volume acceleration (MA) is a very sensitive index of LV contractility. MA occurs in the earliest phase of ejection during which blood receives kinetic energy and inertia. Our method and study, by routinely using left cine-ventriculography enables one to follow the shape, the size and the way of motion of dyed blood in the ascending aorta and that MA and the derived indices (eg. volume velocity, the velocity of ejection, partial ejection fraction etc.) could be reliably calculated by determination of the partial volumes. This method is published in the literature for the first time. The MA results were compared with the MA data obtained by doppler method and EMFM. The sensitivity of MA was tested in comparison with the already introduced indices of preejection and ejection period. It was confirmed that it is possible to calculate MA by cineventriculography. The new approach is physiological and differs considerably from the doppler method and EMFM. The determination of partial volumes and MA is relatively simple. In the study the physical approach was developed. By MA we were able to separate normal from bad ventricles as well as different subgroups of patients. MA turned out to be a more sensitive index of contractility than the indices of preejection and ejection period. The degree of correlation between MA and LV ejection fraction was poor. It was demonstrated that MA depends little on proload, afterload and heart rate (the determinants of stroke volume). By qualitative analysis the data on ejection patterns in the earliest phase of ejection were obtained.(trunc.)
Descriptors     CORONARY DISEASE
MYOCARDIAL CONTRACTION
HEART VENTRICLE
CINERADIOGRAPHY
HEART CATHETERIZATION
STROKE VOLUME
AGE FACTORS