Author/Editor		Finderle, Ž; Cankar, K; Šebeštjen, M; Keber, I
Title		The effect of fenofibrat and cerivastatin on endothelium dependent and independent vasodilatation
Type		članek
Source		In: Fagrell B, editor. 21st European conference on microcirculation; 2000 Jun 4-7; Stockholm. Bologna: Monduzzi editore,
Publication year		2000
Volume		str. 27-32
Language		eng
Abstract		The effects of cerivastatin or fenofibrat therapy on macrocirculatory and microcirculatory endothelium dependent and independent vasodilatation were studied. Thirty-eight men with combined hyperlipidemia entered the study and were randomized in two groups. After 12 weeks of therapy with either cerivastatin or fenofibrat macrocirculatory endothelium dependent and independent vasodilatation increased significantly. Cerivastatin caused significantly greater increase in endothelium dependent vasodilatation as compared to fenofibrat. On the contrary, no statistically significant change was observed in the microcirculation with either cerivastatin or fenofibrat therapy.
Descriptors		VASODILATION ENDOTHELIUM, VASCULAR HYPERLIPIDEMIA PROCETOFEN HYDROXYMETHYLGLUTARYL COA REDUCTASES MIDDLE AGE MICROCIRCULATION BRACHIAL ARTERY CHOLESTEROL LIPOPROTEINS, HDL CHOLESTEROL LIPOPROTEINS, LDL CHOLESTEROL TRIGLYCERIDES LASER-DOPPLER FLOWMETRY PYRIDINES