Author/Editor		Kopčavar-Guček, Nena; Beović, Bojana
Title		Vpliv cepljenja proti gripi na okužbe dihal v splošni ambulanti
Translated title		Effect of vaccination against influenza on respiratory tract infections
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 70, št. 3
Publication year		2001
Volume		str. 129-32
Language		slo
Abstract		Background. The aim of the study was to evaluate the efficacy of vaccination in our environment. Patients and methods. A group of 60 patients was randomly chosen from among the ones vaccinated in outpatient clinic Zdravje in the fall of 1996. The control group was selected from the non-vaccinated patients of the same clinic. The groups were matched for gender, age, profession and chronical ilnesses. A questionnaire was mailed to all participants inquiring about the respiratory tract infections in the period of observation, i.e. from January 1, 1997 to April 31, 1997. Some of the answers were doublechecked in the medical records of the participants. Chi square test was used to analyse the answers and p + 0.05 was set as the limit. Results. 51 (85%) of the vaccinated and 38 (63%) of the control group responded. The average number of consultations with the physician concerning respiratory tract infections in the vaccinated group was significantly lower than the same parameter in the control group (0.33 consulattions per person in the vaccinated group versus 0.71 consultations per person in the non-vaccinated). 62% of the ones whose family members also received vaccine, reported no upper respiratory tract infections while only 13.6% of the "lone vaccinated" in the family environment remained well. The side effects were described by 4 (7.84%) vaccinated participants, while 9 (23.68%) nonvaccinated declared that the fear of side effects prevented them from the vaccination. Although both groups agreed that the price of the vaccine was reasonable (88.24% of the vaccinated and 60.23% of the control), only 26% of the control group declared the intention to vaccinate in the coming season. Conclusions. The results of the study confirm good efficacy of the vaccination against influenza on the frequency of respiratory tract infections, especially in families where more members are vaccinated. (Abstract truncated at 2000 characters).
Summary		Izhodišča. Z raziskavo smo želeli oceniti uspešnost cepljenja proti gripi in odnos posameznika do cepljenja v našem okolju. Preiskovanci in metode. Po metodi naključnih števil smo izmed pacientov, cepljenih v zavodu Zdravje v času od oktobra do konca decembra 1996 s cepivom proizvajalca Pasteur Merieux, izbrali vzorec 60 preiskovancev. Za kontrolno skupino smo izmed pacientov iste splošne ambulante izbrali 60 necepljenih preiskovancev, ki so se s cepljenimi ujemali v spolu, starosti, poklicu in kroničnih boleznih. Vsem je bil poslan vprašalnik o prebolelih okužbah dihal v času od 1. januarja do 31. aprila 1997. Nekatere odgovore smo preverili v medicinski dokumentaciji sodelujočih. Rezultate smo vrednotili s testom hi-kvadrat s stopnjo tveganja p = 0,05. Rezultati. Odzvalo se je 51 (85%) cepljenih in 38 (63%) necepljenih zavarovancev. Cepljeni so imeli v opazovanem obdobju povprečno 0,33 stika s splošnim zdravnikom zaradi okužbe dihal na preiskovanca, necepljeni pa 0,71, razlika je bila statistično značilna. Med tistimi cepljenimi, pri katerih so se cepili tudi družinski člani, jih kar 62% (18 do 29) ni prebolelo nobene okužbe zgornjih dihal. Cepljeni so med necepljenimi ostali zdravi značilno redkeje (le 13,6% jih ni zbolelo). Stranske učinke so cepljeni opisali v štirih primerih (7,84%), necepljeni pa so strah pred njimi navedli kot osnovni razlog proti cepljenju v devetih primerih (23,68%). Čeprav sta obe skupini označili ceno cepljenja kot primerno (cepljeni v 88,24% in necepljeni v 78,95%) in čeprav sta obe skupini menili, da je cepljenje koristno (cepljeni v 98,04% in necepljeni v 60,23%), je namerno o cepljenju v prihodni sezoni potrdilo le 26% necepljenih v primerjavi z 98,04% cepljenimi. Zaključki. Z rezultati preiskave potrjujemo ugoden vpliv cepljenja na zbolevnost za okužbami dihal, še posebno v družinah, kjer se cepi več družinskih članov. (Izvleček prekinjen pri 2000 znakih.)
Descriptors		INFLUENZA VACCINE RESPIRATORY TRACT INFECTIONS INFLUENZA VACCINATION FAMILY PRACTICE