Author/Editor | Reljič, Milan; Vlaisavljević, Veljko; Gavrić, Vida; Kovačič, Borut; Čižek-Sajko, Mojca | |
Title | Value of the serum estradiol level on the day of human chorionic gonadotropin injection and on the day after in predicting the outcome in natural in vitro fertilization/intracytoplasmic sperm injection cycles | |
Type | članek | |
Source | Fertil Steril | |
Vol. and No. | Letnik 75, št. 3 | |
Publication year | 2001 | |
Volume | str. 539-43 | |
Language | eng | |
Abstract | Objective: To predict the risk of premature ovulation and possibility of pregnancy in natural IVF/ICSI cycles on the basis of the estradiof (E2) level on the day of hCG injection and on the day after. Design: A prospective study. Setting: Hospital research program. Patient(s): One hundred sixty-four women undergoing 305 IVF/ICSI natural cycles. lntervention(s): Serum E2 levels were measured - 12 h before (day 0) and 12-17 h after hCG administration (day 1). Main Outcome Measure(s): E2 levels on day 0 and day 1, the ratio of the day l to day 0 levels, and cycle outcome. Result(s): In cycles with premature ovulation and in conception cycles, the average E2 level on day 0 was statisticaliy significantly higher than in other cycles; whereas the E2 ratio was statistically significantly lower. Muitiple logistic regression was used to determine the connection of the E2 level on day 0 (B0 =-0.742; B =2.147, P =.01) and the E2 ratio (B0=-0.742, B =-3.135; P<.001) with premature ovulation. Only the E2 ratio B0 = 0.659, B = -2.209, P=.0068) was significantly connected with conception. Conclusion(s): In predicting the outcome of natural IVF/ICSI cycles, the importance in the E2 level on the day of hCG administration or on the day after, but rather in the E2 ratio. | |
Descriptors | FERTILIZATION IN VITRO ESTRADIOL OVULATION INDUCTION GONADOTROPINS, CHORIONIC OVUM IMPLANTATION MENSTRUAL CYCLE SPERMATOZOA OOCYTES LOGISTIC MODELS |