Author/Editor		Vodopivec-Jamšek, Vlasta
Title		Antiagregacijsko zdravljenje v ambulanti družinskega zdravnika
Translated title		Antiplatelet therapy in family practice
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 40, št. Suppl 1
Publication year		2001
Volume		str. 119-23
Language		slo
Abstract		Antiplatelet drugs are used for the prevention of complications of atherosclerosis by influencing primarily arterial thrombi. The most frequently administered antiplatelet drug is acetylsalicylic acid. In adition, dipyridamol, ticlopidine and clopidogrel are also prescribed. Important complications associated with the use of acetlysalicylic acid include gastrointestinal hemorrhages. The most dangerous complications of ticlopidin treatment are neutropenia and thrombotic thrombocytopenic purpura. Clopidogrel is safer but more expensive. The paper presents the recommendations for antiplatelet therapy, which are specifically important in family medicine. Good management of antiplatelet treatment requires knowing the recommendations and implementing them in practice (patient selection and motivation, treatment of complications and proper management of documentation), and also, from time to time, monitoring of the quality of work.
Summary		Antiagregacijska zdravila služijo preprečevanju zapletov ateroskleroze in skušajo vplivati predvsem na arterijske strdke. Najpogosteje uporabljeno antiagregacijsko zdravilo je acetilsalicilna kislina, poleg tega predpisujemo še dipiridamol, tiklopidin in v zadnjem času tudi klopidogrel. Pomembni zapleti zdravljenja z acetilsalicilno kislino so krvavitve v prebavilih. Resna zapleta zdravljenja s tiklopidinom sta nevtropenija in trombotična trombocitopenična purpura. Klopidogrel je varnejše, a tudi dražje zdravilo. Predstavljena so priporočila za antiagregacijsko zdravljenje; ki so pomembna za družinsko medicino. Dobro vodenje antiagregacijskega zdravljenja obsega poznavanje priporočil, uvajanje priporočil v prakso (izbira in motivacija bolnikov, ukrepi ob zapletih, vodenje dokumentacije) in občasno spremljanje kakovosti dela.
Descriptors		THROMBOEMBOLISM PLATELET AGGREGATION INHIBITORS ASPIRIN DIPYRIDAMOLE TICLOPIDINE CORONARY DISEASE