Author/Editor		Zabavnik-Piano, Jelka
Title		Sporazumevanje med celicami: družina celičnih receptorjev s sedmimi membranskimi odseki
Translated title		Cell communications: a family of cell receptors with seven membranous parts
Type		članek
Source		Proteus
Vol. and No.		Letnik 63, št. 3
Publication year		2000
Volume		str. 109-15
Language		slo
Abstract		An organisms cells from a system of interacting communications enabling responses to external stimuli as well as to endogenous needs and cell actions. Cells communicate with the help of messenger molecules. Some are small and lipid which can freely cross the cell membrane but large and hydrophobic ones are insoluble in the two-layered membrane, and send their message through receptors buried in the membrane. The activated receptors then direct them to specific cellular effecters that start the cells response. Three basic families of membrane receptors are known: those that function as ion channels, those that function as enzymes, and the G-protein-coupled receptors-GPCR. We describe the characteristics of GPCR, some methods of studying them, and their importance in biomedicine.
Descriptors		CELL COMMUNICATION RECEPTORS, CELL SURFACE GTP-BINDING PROTEINS CLONING, MOLECULAR