Author/Editor		Takač, I; Arko, D; Bali, R; Čas-Sikošek, N; Gorišek, B; Kodrič, T; Zukanović, D
Title		Cervical intraepithelial neoplasia and Chlamydia trachomatis infection
Type		članek
Source		In: Di Paola G, Sardi J, editors. Gynecologic oncology issues in the 8th IGCM meeting of Buenos Aires; 2000 Oct 22-26; Buenos Aires. Bologna: Monduzzi editore,
Publication year		2000
Volume		str. 165-8
Language		eng
Abstract		In the present study we compared the frequency of Chlamydia trachomatis (CT) in patients with cervical intraepithelial neoplasia (CIN) and in women without cervical pathology. In a study group of 423 patients with histologically proven CIN and in 108 controls with normal cervical smear, cytological material for direct immunofluorescence analysis was obtained. Among 423 patients, 24 (5.7%) had CIN 1, 108 (25.5%) CIN 2 and 291 (68.8%) CIN 3. Among all patients with CIN, 27 (6.4%) were CT positive and 396 (93.6%) CT negative. In the control group 6 (5.6%) were CT positive and 102 (94.4%) CT negative. The difference between CT infection incidence in patients with CIN and in women without cervical pathology was not significant (x2=0.29; P> 0.05). In this study, no difference in CT infection incidence was detected between patients with CIN and women with normal cervical smears. The impact of CT infection seems not to interfere with the development or even the promotion of CIN.
Descriptors		CERVICAL INTRAEPITHELIAL NEOPLASIA CHLAMYDIA INFECTIONS CHLAMYDIA TRACHOMATIS VAGINAL SMEARS CONIZATION