Author/Editor		Repše, A; Juvan, R; Križman, I; Repše, S
Title		Predictive factors for regional lymph node involvement in early gastric cancer patients
Type		članek
Source		In: Brennan MF, Karpeh MS, editors. 4th international gastric cancer congress; 2001 Apr 30-May 2; New York. Bologna: Monduzzi editore,
Publication year		2001
Volume		str. 849-53
Language		eng
Abstract		The number of early gastric cancer patients treated endoscopically has been growing constantly since the first presentation of endoscopic mucosal resection as a possibility for radical treatment. 158 early gastric cancer patients were treated in University Medical Center Ljubljana from Jan 1st 1983 to Dec 31st 1997; 156 patents were operated on, 2 were treated endoscopically. 24 out of 156 (15,4%) resected patients had positive regional lymph nodes. Multivariate analysis proved the depth of infiltration (p=0,005), the histological type by Lauren (p=0,0087)and partly the size of the lesion (p=0,1355) to be important as independent prognostic factors for regional lymph node involvement. Observed 5-year survival rate in our patients was 81,7% (85,7% in N0 and 53,3% in N+ patients). Endoscopic mucosal resection is the treatment of choice in early gastric cancer patients with no regional lymph node metastases. Proper selection of patients by clinico-pathological predictive factors for regional lymph node metastases is essential. In our 15-year series besides two endoscopically treated patients another 12 patients fulfilled the criteria for such a therapeutic procedure. None of them had positive regional lymph nodes.
Descriptors		STOMACH NEOPLASMS LYMPHATIC METASTASIS SURGERY, ENDOSCOPIC NEOPLASM STAGING SURVIVAL ANALYSIS LOGISTIC MODELS