Author/Editor     Serša, Gregor; Čufer, Tanja; Čemažar, Maja; Reberšek, Martina; Rudolf, Zvonimir
Title     Electrochemotherapy with bleomycin in the treatment of hypernephroma metastasis: case report and literature review
Type     članek
Source     Tumori
Vol. and No.     Letnik 86, št. 2
Publication year     2000
Volume     str. 163-5
Abstract     A metastasis of hypernephroma was treated by electrochemotherapy with bleomycin. Electrochemotherapy consists of chemotherapy followed by local application of electric pulses to the tumor in order to increase drug delivery to the cells. In the course of a four-week treatment period, the subcutaneous metastasis of the hypernephroma was treated with three sessions of electrochemotherapy, each consisting of 9-10 runs of 8 electric pulses, 10 min after intravenous injection of bleomycin. This treatment resulted in stabilization of the tumor volume for 12 months, whereas the subcutaneous metastasis next to the electrochemotherapy-treated one that did not receive electric pulses progressed immediately.
Descriptors     CARCINOMA, RENAL CELL
BLEOMYCIN
ELECTROPORATION
SKIN NEOPLASMS
MIDDLE AGE
KIDNEY NEOPLASMS
DRUG DELIVERY SYSTEMS