Author/Editor | Weygand-Ðurašević, Ivana; Lenhard, Boris; Filipić-Ročak, Sanda; Rokov, Jasmina; Landeka, Irena; Mijaković, Ivan | |
Title | Organellar and cytosolic seryl-tRNA syntheses: structural, functional and evolutionary aspects | |
Translated title | Strukturni, funkcionalni in evolucijski vidiki organelskih in citosolskih seril-tRNA sintetaz | |
Type | članek | |
Source | Acta Biol Slov | |
Vol. and No. | Letnik 43, št. 1-2 | |
Publication year | 2000 | |
Volume | str. 109-16 | |
Language | eng | |
Abstract | The aminoacyl-tRNA synthetases are large family of house-keeping enzymes esential for translation of genetic information. In eukaryotic cells they are found in cytosol amd in all protein-synthetizing organogelles. In our study of the structure/function relationships in the family of serine specific aminoacyl-tRNA synthesis, we have focused on identifting structuraly based differences in the mechanism of serylation performed by organellar and cytosolic enzymes. | |
Summary | Aminoacil-tRNA sintetaze so velika družina encimov, ki so nujno potrebni za pravilno translacijo genetske informacije. V evkariotskih celicah jih najdemo v citosolu in v vseh organelih, ki sintetizirajo proteine. V naših raziskavah zveze med strukturo in funkcijo v družini serinsko specifičnih aminoacilnih-tRNA sintetazmo se osredotočili na ugotavljanje strukturno pogojenih razlik med organelnimi in citosolnimi encimi pri pripenjanjuu serinskega ostanka na tRNA. | |
Descriptors | RNA, TRANSFER, SER ORGANELLES LEUCINE AMINOPEPTIDASE YEASTS AMINO ACIDS |