Author/Editor		Jordanova, Vesna; Dernovšek, Mojca Z
Title		Odtegnitvena reakcija po prekinitvi zdravljenja z antidepresivi, nevroleptiki in antiholinergičnimi antiparkinsoniki
Translated title		Withdrawal reaction after discontinuation of therapy with antidepressants, neuroleptics and anticholinergic antiparkinsonics
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 70, št. 5
Publication year		2001
Volume		str. 291-4
Language		slo
Abstract		Background. A withdrawal reaction after reduction of dosage or discontinuation of antidepressants, neuroleptics and anticholinergic antiparkinsonics is often neglected in everyday clinical practice. Although neuroleptics and antidepressants do not cause dependence, withdrawal reaction is present in almost one third of patients, but is usually mild. In severe cases the withdrawal reaction might be misdiagnosed, which leads to inappropriate management. Conclusions. Prevalence, clinical characteristics and some etiological hypotheses of withdrawal reaction for antidepressants, neuroleptics and anticholinergic antiparkinsonics are presented in a form to be useful in everyday clinical practice.
Summary		Izhodišča. Prispevek obravnava v klinični praksi pogosto prezrte odtegnitvene reakcije po zmanjšanju odmerka ali ukinitvi antidepresivov, nevroleptikov in antiholinergičnih antiparkinsonikov. Čeprav nevroleptiki in antidepresivi ne povzročajo odvisnosti, lahko odtegnitvene reakcije po prekinitvi zdravljenja srečamo pri skoraj tretjini bolnikov. Odtegnitvene reakcije so večinoma zelo blage, vendar pa je pri zelo izraženih kliničnih slikah včasih težko postaviti pravo diagnozo in ustrezno ukrepati. Zaključki. Prispevek navaja pogostost, klinične slike in nekatere hipoteze o nastanku odtegnitvene reakcije pri antidepresivih, nevroleptikih in antiholinergičnih antiparkinsonikih ter priporoča ukrepe za vsakodnevno klinično delo.
Descriptors		SUBSTANCE WITHDRAWAL SYNDROME ANTIDEPRESSIVE AGENTS ANTIPSYCHOTIC AGENTS ANTIPARKINSON AGENTS