Author/Editor		Meden-Vrtovec, Helena
Title		Hormonsko nadomestno zdravljenje na sekundarni ravni
Translated title		Hormonal replacement therapy on secondary level
Type		članek
Source		Zdrav Vars
Vol. and No.		Letnik 40, št. 7-8
Publication year		2001
Volume		str. 231-5
Language		slo
Abstract		In the introduction the article considers the dilemmas about hormonal replacement therapy in postmenopause. The factors, contributing to the formation of neurovegetative symptoms are presented, together with the description of psychical and physical changes in postmenopause. In postmenopausal period hormonal replacement therapy can be introduced as a short-term treatment of neurovegetative symptoms or as a long-term therapy, preferentially in the women with higher risk to develop osteoporosis and cardiovascular diseases. All types of available hormonal replacement therapy are presented, including estrogens, gestagens, estrogen-gestagen combined preparations and those for local application. In specific, precisely determined indications (low libido, adynamia, apathy), treatment with androgens is also reasonable. Hormonal replacement therapy can not totally replace the ovarian function, but it can alleviate postmenopausal symptoms and improve the quality of life in general.
Summary		V prispevku so uvodoma prikazane dileme o tem, ali naj bi se v pomenopavznem obdobju uporabljalo hormonsko nedomestno zdravljenje. Opisani so dejavniki, ki oblikujejo pomenopavzno nevrovegetativno simptomatiko, hkrati s prikazom telesnih in duševnih sprememb v pomenopavzi. Hormonsko nadomestno zdravljenje v pomenopavzi je lahko uvedeno kot kratkoročno za preprečevanje nevrovegetativne simptomatike ali dolgoročno, zlasti pri ženskah z večjim tveganjem za razvoj osteoporoze in bolezni srca in ožilja. Prikazane so vse oblike uporabe hormonskega nadomestnega zdravljenja in nam dostopni estrogeni, gestageni, estrogensko-gestagenski in kombinirani pripravki ter prejemki za lokalno uporabo. Pri specifičnih, natančno opredeljenih indikacijah (zmanjšanje libida, adinamija, apatija) je utemeljena tudi uporaba androgenov. Hormonsko nadomestno zdravljenje ne more nadomestiti delovanja jajčnikov, lahko po omili pomenopavzne simptome in bistveno izboljša splošno kakovost življenja.
Descriptors		CLIMACTERIC ESTROGEN REPLACEMENT THERAPY