Author/Editor     Završnik, Matej
Title     Ateroskleroza in sladkorna bolezen tipa 2
Translated title     Atherosclerosis and diabetes mellitus type 2
Type     članek
Source     In: Hojs R, Krajnc I, Pahor A, editors. Zbornik predavanj in praktikum 12. srečanje internistov in zdravnikov splošne medicine Iz prakse za prakso z mednarodno udeležbo; 2001 maj 11-12; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year     2001
Volume     str. 109-26
Language     slo
Abstract     Diabetes mellitus is one of the most common chronic diseases in the world. Its predominant clinical form is type 2, which is associated with increased rate of cardiovascular disease: In most studies diabetes is associated with two to three times higher risk of coronary heart disease, which is greater in women than in men. The increased risk cannot be explained only with classical risk factors, which usually combine in diabetics. Hyperglycaemia is very important for microvascular complications, although it is not completely clear to what extent it predicts cardiovascular mortality and morbidity. Hypertrigliceridaema with low cholesterol in high-density lipoproteins and practical normal values of cholesterol in low-density lipoproteins is significant for diabetic dislipidaemia. Quantitative changes in lipids are greater than qualitative. They are very atherogenic: High blood pressure, which also substantially raises the risk of .cardiovascular disease, is important: Additional risk factors are coagulation abnormalities obesity and smoking. It is surprising that diabetics without pre-existing vascular disease run a similar risk of future coronary heart disease events as patients with pre-existing vascular disease: It is therefore necessary to lower risk factors in diabetics as aggressively as is recommended for patients with established coronary disease without diabetes mellitus.
Descriptors     DIABETES MELLITUS, NON-INSULIN-DEPENDENT
ATHEROSCLEROSIS
RISK FACTORS
HYPERGLYCEMIA
HYPERLIPIDEMIA
HYPERTENSION
OBESITY
SMOKING