Author/Editor		Petelin, M; Skalerič, U
Title		Osteoporoza in parodontalna bolezen
Translated title		Osteoporosis and periodontal disease
Type		članek
Source		Zobozdrav Vestn
Vol. and No.		Letnik 56, št. 3-4
Publication year		2001
Volume		str. 79-85
Language		slo
Abstract		Osteoporosis and periodontitis affect large numbers of women and men. The incidence of these diseases increases with advancing age. Osteoporosis is characterised by low bone mass with a consequent increase in fracture risk. Periodontitis is an inflammatory reaction of the supporting tissues of teeth, which results in resorption of alveolar bone accompanied by loss of clinical attachment, and is a major cause of tooth loss. This review article examines the relationships between osteoporosis, alveolar bone loss and periodontal disease. Osteoporosis/osteopoenia and oestrogen deficiency are risk factors for alveolar bone density reduction in postmenopausal women with a history of periodontitis. Women suffering from osteoporosis have higher average tooth loss than healthy women. In an animal model, alveolar bone loss produced by oestrogen deficiency was associated with elevated IL-6 cytokine levels in gingival tissues. Hormone replacement therapy of osteoporosis affects salivary calcium concentrations, suggesting that the effect of the treatment on general calcium turnover is also reflected in saliva.
Descriptors		OSTEOPOROSIS PERIODONTAL DISEASES RISK FACTORS BONE DENSITY BONE RESORPTION TOOTH LOSS ALVEOLAR BONE LOSS