Author/Editor		Keše, Darja; Čižman, Milan; Marin, Jožica
Title		Chlamydia pneumoniae - prevalenca protiteles pri zdravi populaciji in bolnikih z doma pridobljeno pljučnico
Translated title		Chlamydia pneumoniae - the prevalence of antibodies in healthy population and patients with community acquired pneumonia
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 70, št. 6
Publication year		2001
Volume		str. 329-33
Language		slo
Abstract		Background. To determinate the prevalence rates of Chlamydia pneumoniae infections in Slovenia and to evaluate the importance of C. pneumoniae infections at patients with community acquired pneumonia (CAP). Materials and methods. With the microimmunofluorescence test (micro-IF) we evaluated the presence of C pneumoniae specific antibodies in 1036 healthy subjects, in two periods of time, in 1991-93 and 1997-1998. We also tested the pair sera collected from 2118 patients with CAP between 1993-1999. Results. We demonstrated that C. pneumoniae infections are common in our population, as we detected IgG antibodies in 43.1% of healthy population. The prevalence rate of C. pneumaniae infectians statistically significant increased in two periods of time. Acute C. pneumoniae infections were proved in 15.9% of all patients with CAP. Conclusions. C. pneumoniae is important respiratory pathogen also in aur community. The infections are more common in older patients. Because C. pneumoniae like other Chlamydia species has tendency to cause chronic disease, it is reasonable to diagnose this bacterium in respiratory patients. It is also recommended to test canvalescent sera at serologic laboratory diagnosis.
Summary		Izhodišča. Da bi ugotovili razširjenost okužb z bakterijo Chlamydia pneumoniae v Sloveniji in ovrednotili njen pomen pri bolnikih z doma pridobljeno pljučnico. Materiali in metode. V serumih 1038 asimptomatskih oseb smo ugotavljali protitelesni imunski odziv proti C. pneumoniae z metodo mikroimunofluorescence, in sicer v obdobju 1991-93 in v letih 1997-98. Prav tako smo preiskali parne serume 2118 bolnikov z doma pridobljeno pljučnico, zbrane v obdobju 1993-1999. Rezultati. Ugotovili smo, da so tudi pri nas okužbe s C. pneumoniae razmeroma pogoste, saj smo protitelesa IgG dokazali pri 43,1% pregledane populacije. Prekuženost prebivalcev v dveh ločenih obdobjih se je statistično značilno povečala. Akutno okužbo s C. pneumoniae smo dokazali pri 15,9% bolnikov z doma pridobljeno pljučnico. Zaključki. C. pneumoniae je pomemben povzročitelj bolezni dihal tudi v našem prostoru. Okužbe so pogostejše pri odraslih bolnikih. Glede na to, da C. pneumoniae izraža tendenco po povzročanju kroničnih okužb, je smiselno iskanje tega povzročitelja pri bolnikih. Prav tako moramo ob uporabi serološkega testa mikro-lF vedno pregledati tudi serum, odvzet v konvalescentni stopnji bolezni.
Descriptors		CHLAMYDIA PNEUMONIAE CHLAMYDIA INFECTIONS ANTIBODIES, BACTERIAL IGG COMMUNITY-ACQUIRED INFECTIONS