Author/Editor		Novak-Grubič, Virginija
Title		Suradnja shizofrenih bolesnika pri dugotrajnom liječenju neurolepticima
Type		monografija
Place		Zagreb
Publisher		Sveučilište u Zagrebu, Medicinski fakultet
Publication year		2000
Volume		str. 79
Language		cro
Abstract		Advances in psychopharmacology enable better therapeutic efficacy and prevention of replase of schizophrenia. Unfortunately many patients refuse to take the prescribed drugs and drop out of treatment after being discharged from the hospital. Many factors influencing non-compliance have been identified. However, the studies have a variety of methodological differences, so the results are hard to compare. The aim of our study was to identify factors influencing non-compliance in a group of first admitted patients with schizophrenia, schizophreniform disorder and schizoaffective disorder. Fifty-six patients were enrolled in the prospective study at the Ljubljana Psychiatric Clinic and the correlation between demographic and disease-related factors to compliance was assessed. We included first-time admitted male patients under same treatment conditions. Psychopathological symptoms and extrapyramidal side effects were assessed with PANSS, Simpson-Angus Scale and Barnes Akathisia Scale at admission and discharge. Patients were followed up for one year after discharge. Non-compliance was defined as dropping out of treatment (at least one missed appointment). Predictors of non-compliance were identified with Cox survival analysis. Thirty patients (53,6%) dropped out of treatment in the first year, most of them in the first three months. Non-compliance was associated with diagnosis of schizophrenia vs. diagnosis of schizoaffective and schizophreniform disorder. Positive symptoms at admission and lack of insight at discharge were also combined with non-compliance. Sociodemographic factors and extrapyramidel side effects were not related to non-compliance.
Descriptors		SCHIZOPHRENIA HOSPITALIZATION ANTIPSYCHOTIC AGENTS LENGTH OF STAY PATIENT ACCEPTANCE OF HEALTH CARE FAMILY BASAL GANGLIA DISEASES PARKINSON DISEASE