Author/Editor		Terzič, Dragan
Title		Zdravljenje rezistentnih depresij in primer uspešne uporabe donepezil HCl v njihovi obravnavi
Translated title		Treatment od resistant depressions and case of successful use of donepezil HCl in their therapy
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 70, št. 7-8
Publication year		2001
Volume		str. 415-7
Language		slo
Abstract		Background. In this article some approaches how to treat a stadium of resistant depression are described. There is aslo a description of the successful use of inhibitors acetylholinesterase donepezil hydrochloride (Aricept) in treatment of this kind of depression. Taking into account a great number of depressive patients who are resistant to usual antidepressivs these new approaches to treatment are of a great importance due to the fact that in many cases previous treatments of a depressive patients proved to be unsuccessful. This article is considered to be one of the first description in respect of the use of inhibitors of acetylcholinesterase in treatment of resistant depressions. Conclusions. In case of resistant depressions one of the possibilities of its treatment is the use of inhibitors of acetylcholinesterase (and may be others) in combination with antidepressants.
Summary		Izhodišča. V pričujočem članku so opisane možnosti zdravljenja rezistentnih depresij in primer uspešne uporabe inhibitorja acetilholinesteraze donepezil hidroklorida (Aricept) v njihovi uporabi. Glede na veliko število depresivnih bolnikov, rezistentnih na antidepresive, so novi pristopi za zdravljenje omenjene oblike bolezni velikega pomena, saj je kljub številnim možnostim veliko število bolnikov neuspešno zdravljenih. To je eden od prvih opisov uporabe inhibitorjev acetilholinesteraze v zdravljenju rezistentnih depresij. Zaključki. V primeru rezistentnih depresij je ena izmed možnosti uporaba inhibitorjev acetilholinesteraze donepezila HCI (in morda drugih) v kombinaciji z antidepresivi.
Descriptors		DEPRESSIVE DISORDER CHOLINESTERASE INHIBITORS DRUG RESISTANCE