Author/Editor		Parežnik, Roman; Voga, Gorazd; Podbregar, Matej; Krivec, Bojan; Skale, Rafael; Gabršček, Lucija
Title		Sepsa na internističnem intenzivnem oddelku: osamitev večkratno odpornih bakterij iz krvi
Translated title		Sepsis in a medical intensive care unit: multi-antibiotic resistant bacteremia
Type		članek
Source		In: Lešničar G, editor. Infektološki simpozij. Zbornik predavanj ob 40-obletnici ustanovitve infektološke sekcije SZD - Združenja za infektologijo SZD; 2001 okt 5-6; Celje. Celje: Splošna bolnišnica Celje,
Publication year		2001
Volume		str. 103-13
Language		slo
Abstract		The objective of our study was to determine the incidence of sepsis and its clinical forms (sepsis, severe sepsis and septic shock), circumstances and source of infection, microbiologic findings, mortality and possible increase in multi-antibiotic resistant microorganisms causing sepsis in the Department for Internal Intensive Care Medicine of the General Hospital Celje. In a retrospective observational study we reviewed the medical records of all patients admited to our department in the years 1998, 1999 and 2000. Among 2035 admited patients sepsis was diagnosed in 197 (9.7%) patients: moderate sepsis in 5 (0.3%), severe sepsis in 34 (1.7%) and septic shock in 159 (7.8%) patients. Nosocomial infection was present in 55 (28%) of patients with sepsis. Source of infection was identified in 174 (89%) patients (respiratory tract 35%, abdomen 22%, urinary tract 17%, skin and soft tisues 6%, vascular catheter 4%, meningae 1%, female genital tract 0.5%, unknown source 12%). Infection was microbiologically confirmed in 127 (64%) patients and bacteremia in 80 (42%) patients. In patients with sepsis and bacteremia mufti-antibiotic resistant bacteria were isolated in 12 (15%) patients. The proportion of patients with mufti-antibiotic resistant bacteremia did not significantly change during the obsevational period. Intensive-care-unit-acquired infection was the only independent risk factor for mufti-antibiotic resistant bacteremia (p=0.02). Of all the septic patients 114 (58%) died in the ICU and additional 19 (9.6%) died before discharge from hospital, i.e. altogether 133 (67%) patients: The mortality in patients with bacteremia was significantly lower than in patients without bacteremia. Detection of mufti-antibiotic resistant bacteremia had no significant impact on the mortality rate. (Abstract truncated at 2000 characters)
Descriptors		SEPSIS INTENSIVE CARE UNITS SHOCK, SEPTIC DRUG RESISTANCE, MULTIPLE INCIDENCE