Author/Editor		Periš, Z
Title		Dermoabrasion - method of choice in treatment of morbus Darier
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 10, št. 3
Publication year		2001
Volume		str. 111-6
Language		eng
Abstract		Presented are patients with typical changes in morbus Darier, successfully treated with the method of deep abrasion. After experimental abrasions the regenerated epidermis revealed all the characteristics of morbus Darier, while the regenerated epidermis after deep abrasion, when the regeneration resulted from remnants of epidermal adnexes, became completely normal both clinically and pathohistologically. Abrasion of large surfaces is performed under complete anesthesia. Morbus Darier is the only hereditary keratoderma in which after deep dermoabrasion the clinically and pathohistologically normal epidermis is regenerated and remains permanently unchanged. A highly probable explanation is that during the embriogenesis the epithelial adnexes had been formed before the pathological process characteristic for morbus Darier started.
Descriptors		KERATOSIS FOLLICULARIS DERMABRASION TREATMENT OUTCOME