Author/Editor		Vlaisavljević, V; Kovačič, B; Gavrič-Lovrec, V; Reljič, M
Title		Simplification of the clinical phase of IVF and ICSI treatment in programmed cycles
Type		članek
Source		Int J Gynecol Pathol
Vol. and No.		Letnik 69, št. 2
Publication year		2000
Volume		str. 135-42
Language		eng
Abstract		Objective: To evaluate the success of a protocol for controlled ovarian hyperstimulation allowing patient self-selection into groups for ovulation stimulation planned 8 weeks and more in advance following rycle synchronization, drug self-administration as well as a reduced number of folliculometries. Methods: A total of 714 patients received the same stimulation protocol. In 260 cases GaRH-a was applied daily and in 454 as depot. In all patients FSH-HP was self-administered subcutaneously for ovarian stimulation. In 316 patients IVF and in 398 patients ICSI was performed. Results: The delivery rate per started cycle was higher in patients receiving depot GnRH-a in the IVF and ICSI group (30.2 vs. 23.4) than in those receiving subcutaneous GnRH-a (20.2 vs. 22.1). Conclusion: Programming of the IVF/ICSI cycle greatly simplifies treatment. A comparison of pregnancy rate and delivery rate per cycle between depot and subcutaneous daily application of GnRh-a did not confirm any statistically significant difference.
Descriptors		FERTILIZATION IN VITRO OVULATION INDUCTION OOCYTES OVARIAN HYPERSTIMULATION SYNDROME GONADORELIN PREGNANCY TREATMENT OUTCOME