Author/Editor		Fišer, Jerneja; Špacapan, Suzana; Prinčič, Dragica; Frelih, Tatjana
Title		Odkrivanje kolonizacije nosečnic z bakterijo Streptococcus agalactiae v severno primorski regiji
Translated title		Detection of colonization of pregnant women with Streptococcus agalactiae in the Northprimorska region
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 70, št. 11
Publication year		2001
Volume		str. 623-6
Language		slo
Abstract		Background. Streptococcus agalactiae (GBS) is a leading cause of neonatal sepsis and meningitis. Newborns are colonized with GBS at the time of delivery. Since vertical transmission from colonized mother to infant is required for the development of disease, the aim of our study, Detection of Colonization of Pregnant Women with Streptococcus agalactiae in the Severnoprimorska Region was to determine the rate of vaginal and rectal GBS colonization of pregnant women. Methods. Methods of GBS detection were derived from the 1996 CDC (Centers for Disease Control and Prevention) guidelines (1), recommending taking the vaginal and rectal smears of pregnant women between 3th and 37th weeks of pregnancy and use of selective broth. Our one-year study (from the beginning of April 1999 to the end of April 2000) was at first intended to include only pregnant women between 35th and 37th weeks of pregnancy to whom two smears were taken, but gynaecologists, although they were given exact instructions, often took smears before 35th or after 37th week of pregnancy, or indicated no week of pregnancy; moreover, to 30 pregnant women they only took one smear. We therefore decided to include these pregnant women in our study, too. After taking the smears the gynaecologists put the swabs in a selective broth medium with antibiotics and immediately sent them to the microbiology laboratory for GBS identification. Results. 830 pregnant women were examined for GBS; in 800 cases 2 smears were taken, in 30 cases only the vaginal smear. 567 women were examined between 35th and 37th weeks of pregnancy, 22,3% were colonized with GBS; 201 women were examined between 30th and 34th week, 25.8% were colonized with GBS. Of all 830 pregnant women examined 192 women (more than 23%) were found colonized with GBS; 12% had GBS in both vagina and rectum, 7.3% only in the vagina and 3.7% only in the rectum. (Abstract truncated at 2000 characters)
Summary		Izhodišča. Streptococcus agalactiae (GBS) je eden glavnih povzročiteljev sepse in meningitisa pri novorojenčkih. Novorojenček se kolonizira z GBS med prehodom skozi porodni kanal kolonizirane matere. Ker je za bolezen nujen vertikalni prenos s kolonizirane matere na otroka, smo v nalogi z naslovom Odkrivanje kolonizacije nosečnic z bakterijo Streptococcus agalactiae v severnoprimorski regiji ugotavljali kolonizacijo nosečnic z GBS v nožnici in rektumu. Metode. Način odkrivanja GBS pri nosečnicah smo povzeli po smernicah Centra za preprečevanje in nadzor bolezni iz ZDA (CDC) iz leta 1996 (1), ki priporoča odvzem brisa nožnice in brisa rektuma pri nosečnicah med 35. in 37. tednom nosečnosti ter uporabo selektivnega tekočega gojišča. V nalogo, ki je trajala od začetka aprila 1999 do konca aprila 2000, smo nameravali vključiti samo nosečnice-med 35. in 37. tednom nosečnosti z dvema odvzetima brisoma, vendar pa so ginekologi kljub natančnim navodilom dostikrat odvzeli brise pred 35, alipo 37. tednu nosečnosti, pri nekaterih niso označili trajanja nosečnosti v času odvzema brisov, 30 nosečnicam pa so advzeli samo en bris. Tako smo se odločili, da v nalogo vključimo tudi te nosečnice. Po odvzemu so brise vložili v tekoče selektivno gojišče z antibiotiki in jih takoj poslali v mikrobiološki laboratorij, kjer smo ugotavljali prisotnost GBS. Rezultati. Na kolonizacijo nosečnic z GBS smo pregledali 830 žensk, 800 nosečnicam so ginekologi odvzeli 2 brisa: bris nožnice in bris rektuma, 30 pa samo bris nožnice. (Izvleček skrajšan pri 2000 znakih).
Descriptors		STREPTOCOCCUS AGALACTIAE VAGINAL SMEARS RECTUM PREGNANCY