Author/Editor		Podbregar, Matej
Title		Metabolism in chronic heart failure leading to cardiac cachexia - pathophysiology
Type		članek
Source		In: Štiblar-Martinčič D, Petrovič D, editors. Cardiovascular diseases. Proceedings of the 32nd memorial meeting devoted to professor Janez Plečnik, International symposium in memory of professor Rene Favaloro; 2001 Dec 6-8; Ljubljana. Ljubljana: Medical faculty,
Publication year		2001
Volume		str. 49-54
Language		eng
Abstract		Cardiac cachexia is independent risk factor for mortality in chronic heart failure. Recent research has emphasized the potential importance of catabolic: anabolic hormone disturbance due to neurohormonal and immune system activation, and shift of total body substrate utilization to less energy-efficient processes in the development of cardiac cachexia and progression of heart failure. In this article the pathophysiological mechanisms of cardiac cachexia will be reviewed, and the role of (3-blockers in improvement of energy-efficiency and reduction of resting energy production rate in chronic heart failure patients will be discussed.
Descriptors		HEART FAILURE, CONGESTIVE CACHEXIA